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Njoku, O. U.
- Anti-Inflammatory Effects of Rothmannia longiflora Fruit Extract
Abstract Views :167 |
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Authors
Affiliations
1 Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, NG
2 Department of Biochemistry, University of Nigeria, Nsukka, NG
3 Department of Anatomy, University of Nigeria Teaching Hospital, Enugu, NG
4 Department of Biochemistry, College of Medical Sciences, Ebonyi State University, NG
1 Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, NG
2 Department of Biochemistry, University of Nigeria, Nsukka, NG
3 Department of Anatomy, University of Nigeria Teaching Hospital, Enugu, NG
4 Department of Biochemistry, College of Medical Sciences, Ebonyi State University, NG
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 4 (2010), Pagination: 327-330Abstract
The anti-inflammatory activity of the fruit extract of Rothmannia longiflora was carried out by evaluating its inhibitory effect on Phospholipase A2 and Prostaglandin Synthetase. As R. longiflora was found to have febrifugal and analgesic properties by reducing oedema formation; the ability of the extract to inhibit the synthesis of prostaglandin which is one of the mediators of inflammation, was utilized as the model for anti-inflammation. R. longiflora was found to significantly (p<0.05) inhibit the activity of both Phospholipase A2 and Prostaglandin Synthetase activities. The results of this study shows the anti-inflammatory activity of R. longiflora extract and suggest further investigations into the effects of specific constituent(s) of the plant on inflammation.Keywords
Rothmannia longiflora, Inflammatory, Prostaglandin Synthetase, Phospholipase A2.- Phytochemical Analysis and Acute Toxicity/Lethality Study of Ethanol Extract of Eugenia uniflora Pulp.
Abstract Views :139 |
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Authors
Affiliations
1 Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, NG
1 Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, NG
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 4 (2010), Pagination: 336-339Abstract
The phytochemical analysis and acute toxicity (LD50) studies were carried out on the ethanol extract of Eugenia uniflora pulp. The phytochemical results showed the presence of alkaloids, glycosides, flavonoids, tannins, saponins and terpenoids. Results of the acute toxicity study gave LD50 value of 2408.3mg/kg.Keywords
Phytochemical Analysis, Acute Toxicity, Eugenia uniflora, Ethanol.- Vitamin and Metal Analyses of Ethanol Extract of Eugenia uniflora Pulp
Abstract Views :212 |
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Authors
Affiliations
1 Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, NG
1 Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, NG
Source
Asian Journal of Research in Chemistry, Vol 3, No 4 (2010), Pagination: 1095-1098Abstract
Some antioxidant vitamins and metals were analysed using ethanol extract sample of Eugenia uniflora pulp. In the vitamin and metal analysis, E. uniflora fruit pulp had higher level of vitamin C compared with β-carotene and vitamin E. The results of the metal analysis also showed higher level of calcium compared with iron, magnesium, zinc and chromium.Keywords
Eugenia uniflora, Vitamin, Metal, Ethanol.- Evaluation of Anti-Inflammatory and Membrane-Stabilizing Property of Methanol Extract of Rothmannia longiflora Fruit
Abstract Views :143 |
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Authors
Affiliations
1 Dept. of Biochemistry, University of Nigeria, Nsukka, Enugu State, NG
2 Department of Anatomy, University of Nigeria, Teaching Hospital, Enugu, NG
1 Dept. of Biochemistry, University of Nigeria, Nsukka, Enugu State, NG
2 Department of Anatomy, University of Nigeria, Teaching Hospital, Enugu, NG